Quality control in molecular genetic testing

E Dequeker; S Ramsden; W W Grody; T T Stenzel; D E Barton

doi:10.1038/35088588

Quality control in molecular genetic testing

Nat Rev Genet. 2001 Sep;2(9):717-23. doi: 10.1038/35088588.

Authors

E Dequeker¹, S Ramsden, W W Grody, T T Stenzel, D E Barton

Affiliation

¹ European Thematic Network for Cystic Fibrosis and European Molecular Genetics Quality Network (EMQN), Department for Human Genetics, University of Leuven, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.

PMID: 11533720
DOI: 10.1038/35088588

Abstract

DNA-based testing for genetic diseases has developed from nothing into a principal part of laboratory medicine over the past 15 years. In the rush to bring these powerful new technologies into medical use, issues of quality have not always been given sufficient attention. Efforts are now being made to assess the quality of the output of genetic testing laboratories, and the results show that there is room for improvement.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Accreditation
European Union
Genetic Diseases, Inborn / diagnosis
Genetic Diseases, Inborn / genetics
Genetic Testing / standards*
Humans
Laboratories / standards
Quality Control*
United Kingdom
United States