Fas-ligand mediated apoptosis in severe sepsis and shock

Scand J Infect Dis. 2003;35(9):593-600.

Abstract

Alterations in the apoptotic process in lymphoid tissues is a common condition which is encountered in the severely septic animal and critically ill patient. Here we attempt to delineate the pathological significance of these apoptotic changes and the role of Fas-FasL mediated contribution to this process.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Apoptosis / immunology
  • Apoptosis / physiology*
  • Fas Ligand Protein
  • Humans
  • Membrane Glycoproteins / physiology*
  • Mice
  • Sepsis / immunology
  • Sepsis / pathology*
  • Shock, Septic / immunology
  • Shock, Septic / pathology*
  • Thymus Gland / pathology

Substances

  • FASLG protein, human
  • Fas Ligand Protein
  • Fasl protein, mouse
  • Membrane Glycoproteins