Abstract
Exposure of human plasma to ozone produces oxidative protein damage, measured as protein carbonyl formation. Isolated human albumin or creatine phosphokinase are oxidized much faster than are total proteins. Consideration must be given to proteins as targets of oxidative injury by ozone in vivo.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Blood Proteins / drug effects*
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Blood Proteins / metabolism
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Creatine Kinase / antagonists & inhibitors
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Creatine Kinase / drug effects
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Creatine Kinase / metabolism
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Free Radicals
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Humans
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In Vitro Techniques
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Male
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Middle Aged
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Oxidation-Reduction
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Ozone / adverse effects*
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Serum Albumin / drug effects
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Serum Albumin / metabolism
Substances
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Blood Proteins
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Free Radicals
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Serum Albumin
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Ozone
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Creatine Kinase