Abstract
PEComas localized in the region of falciform ligament and broad ligament are exceedingly rare. Most of them are built of spindle neoplastic cells. We report a case of epithelioid PEComa of the falciform ligament and/or broad ligament. There is only one report of such neoplasm in English-language literature. Histologically, the tumor was composed of nests of epithelioid clear cells stained positively for vimentin, HMB45, and SMA. Because of morphological features of the tumour (4 mitoses /20HPF, focal necrosis, and vascular invasion) we assess the neoplasm as potentially malignant.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adult
-
Biomarkers, Tumor / analysis
-
Broad Ligament / metabolism
-
Broad Ligament / pathology*
-
Calmodulin-Binding Proteins / genetics
-
Female
-
Gene Rearrangement
-
Humans
-
Immunohistochemistry
-
In Situ Hybridization
-
Perivascular Epithelioid Cell Neoplasms / genetics
-
Perivascular Epithelioid Cell Neoplasms / metabolism
-
Perivascular Epithelioid Cell Neoplasms / pathology*
-
RNA-Binding Protein EWS
-
RNA-Binding Proteins / genetics
Substances
-
Biomarkers, Tumor
-
Calmodulin-Binding Proteins
-
EWSR1 protein, human
-
RNA-Binding Protein EWS
-
RNA-Binding Proteins