A novel alpha-thalassemia-2 (-2.7-kb) observed in a Chinese patient with Hb H disease

Am J Hematol. 1991 Nov;38(3):248-9. doi: 10.1002/ajh.2830380321.

Abstract

We describe a newly detected alpha-thalassemia-2 (alpha-thal-2) deletion characterized by a small -2.7-kb deletion involving the alpha 1 globin gene. This deletion has thus far been observed in only one Chinese subject with Hb H disease.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Asian People*
  • China / ethnology
  • Chromosome Deletion
  • Chromosome Mapping
  • Globins / genetics
  • Humans
  • Thalassemia / ethnology
  • Thalassemia / genetics*

Substances

  • Globins