Abstract
Kasabach-Merritt phenomenon (KMP) is a rare thrombocytopenic consumption coagulopathy associated with an enlarging tufted angioma or kaposiform hemangioendothelioma. We report a case series of patients with KMP and discuss the treatment options and outcomes. Nine patients with a diagnosis of KMP were identified through retrospective chart review-6 had "definite KMP" and 3 had "less likely KMP." The hematologic features of KMP and those of chronic coagulopathy seen with other vascular malformations can be similar, which makes KMP difficult to distinguish.
MeSH terms
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Anti-Inflammatory Agents / therapeutic use
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Antineoplastic Agents / therapeutic use
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Disseminated Intravascular Coagulation / complications*
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Disseminated Intravascular Coagulation / drug therapy
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Disseminated Intravascular Coagulation / physiopathology*
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Female
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Hemangioendothelioma / complications*
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Hemangioendothelioma / drug therapy
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Hemangioma / complications*
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Hemangioma / drug therapy
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Humans
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Infant
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Male
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Radiotherapy
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Skin Neoplasms / complications*
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Skin Neoplasms / drug therapy
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Thrombocytopenia / complications
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Thrombocytopenia / drug therapy
Substances
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Anti-Inflammatory Agents
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Antineoplastic Agents