A copper(I)-ion selective two-photon fluorescent probe for in vivo imaging

Chem Commun (Camb). 2011 Jul 7;47(25):7146-8. doi: 10.1039/c1cc11568e. Epub 2011 May 25.

Abstract

We report a two-photon fluorescent probe (ACu1) that can be excited by 750 nm femto-second pulses, shows high photostability and negligible toxicity, and can visualize Cu(+) distribution in live cells and tissues by two-photon microscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Survival
  • Copper / chemistry*
  • Fluorescent Dyes / chemistry*
  • Fluorescent Dyes / toxicity
  • HeLa Cells
  • Humans
  • Microscopy
  • Molecular Imaging / methods*
  • Photons*

Substances

  • Fluorescent Dyes
  • Copper