Lymphadenopathy, as a complication of gold therapy, appears to be an uncommon occurrence. Lymph node infarction has not been previously documented in this setting. The unique pathologic features in this case may reflect: a phenomenon specific to gold; early examination of the infarcted node; or underlying leukocytoclastic angiitis secondary to gold toxicity. Polymorphonuclear leukocytic infiltration of an infarcted lymph node has apparently not been previously reported.