Neuroendocrine carcinoma arising in an ovarian mucinous cystadenoma

Int J Gynecol Pathol. 1996 Apr;15(2):167-70. doi: 10.1097/00004347-199604000-00012.

Abstract

A case of neuroendocrine carcinomas arising in the form of a mural nodule in an ovarian mucinous cystadenoma is presented. This represents the third case of neuroendocrine carcinoma arising in an ovarian mucinous tumor. The carcinoma cells were moderately to strongly immunoreactive for enolase, keratin, chromogranin, synaptophysin, and focally, neuron-specific enolase, and contained 130-330 nm neurosecretory granules. The patient presented 9 months after surgery with liver metastases and peritoneal implants. She died of disease within 10 months of initial presentation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Neuroendocrine / secondary*
  • Carcinoma, Neuroendocrine / surgery
  • Carcinoma, Neuroendocrine / ultrastructure
  • Cystadenoma, Mucinous / pathology*
  • Cystadenoma, Mucinous / surgery
  • Cystadenoma, Mucinous / ultrastructure
  • Fatal Outcome
  • Female
  • Humans
  • Hysterectomy
  • Immunohistochemistry
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / secondary*
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / surgery
  • Neoplasms, Multiple Primary / ultrastructure
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Ovarian Neoplasms / ultrastructure
  • Peritoneal Neoplasms / diagnostic imaging
  • Peritoneal Neoplasms / secondary*
  • Radiography