The cytogenetical findings in a cultured polymorphous low-grade adenocarcinoma (PLGA) of the minor salivary glands are reported. The deviations observed showed similarities to those found in the only hitherto studied case originating in the minor glands. Both these cases, however, showed a picture completely different from that in the two reported cases of parotid PLGA, constituting the malignant component in carcinomas ex pleomorphic adenoma. The most probably reasons are believed to be aetiological differences.