Hepatic resection is the most curative treatment option for early‐stage hepatocellular
carcinoma, but is associated with a high recurrence rate, which exceeds 50% at 5 years after …

Cancer-associated fibroblasts (CAF) are key contributors to malignant progression, but their
critical regulators remain largely unknown. In this study, we examined the role of Twist1, a …

Next-generation sequencing (NGS) has recently emerged as an essential component of
personalized cancer medicine due to its high throughput and low per-base cost. However …

Objective Lipotoxic hepatocyte injury is a primary event in non-alcoholic steatohepatitis
(NASH), but the mechanisms of lipotoxicity are not fully defined. Sphingolipids and free …

Microfluidic devices as translational research tools provide a potential alternative to animal
experiments due to their ability to mimic physiological parameters. Several approaches that …

Background: Core needle biopsy is a relatively new technique used to diagnose salivary
gland lesions, and its role in comparison with fine needle aspiration cytology needs to be …

OBJECTIVE: Higher level of circulating monocyte has been reported to be related with
higher cancer incidence and mortality. We investigated the role of pre-treatment circulating …

Notwithstanding remarkable treatment success with anti‐PD‐1 monoclonal antibody,
oncogenic mechanism of PD‐L1 regulation in gastric cancer (GC) remains poorly …

Tumor mutation burden (TMB) is an emerging biomarker, whose calculation requires
targeted sequencing of many genes. We investigated if the measurement of mutation counts …

Methods A total of 269 gastric hyperplastic polyps from 216 patients removed by endoscopic
polypectomy (EP) or surgical resection were enrolled in this study, and their endoscopic …