User profiles for "author:F L Pearce"

FL Pearce

Verified email at ucl.ac.uk
Cited by 7462

Mucosal mast cells: III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells

FL Pearce, AD Befus, J Bienenstock - Journal of Allergy and Clinical …, 1984 - Elsevier
Quercetin, a naturally occurring flavonol structurally related to the antiallergic drug disodium
cromoglycate inhibits anaphylactic histamine release from MMC isolated from the small …

Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells.

AD Befus, FL Pearce, J Gauldie… - … (Baltimore, Md.: 1950 …, 1982 - journals.aai.org
We have developed a procedure for the dispersion of mast cells from the intestinal lamina
propria (LP) and epithelium of rats infected with the intestinal nematode, Nippostrongylus …

Human basophil degranulation is not triggered by very dilute antiserum against human IgE

SJ Hirst, NA Hayes, J Burridge, FL Pearce, JC Foreman - Nature, 1993 - nature.com
We have attempted to reproduce the findings of Benveniste and co-workers, who reported in
1988 that degranulation of human basophil leukocytes is triggered by very dilute (102 …

Some characteristics of histamine secretion from rat peritoneal mast cells stimulated with nerve growth factor.

FL Pearce, HL Thompson - The Journal of physiology, 1986 - Wiley Online Library
Nerve growth factor (NGF) isolated from mouse submandibular gland or from snake venom
produced a dose‐dependent release of histamine from isolated rat peritoneal mast cells …

Biological effects of histamine: an overview

FL Pearce - Agents and actions, 1991 - Springer
Conclusion It is now some eighty years since the pioneering studies of Dale, Barger,
Laidlaw and others defined the immediate pharmacological actions of histamine. In that …

Some studies on the release of histamine from mast cells stimulated with polylysine.

M Ennis, FL Pearce, PM Weston - British journal of pharmacology, 1980 - ncbi.nlm.nih.gov
Abstract 1 Polylysine is an extremely potent releaser of histamine from rat peritoneal mast
cells. Isolated mesenteric mast cells of the rat also respond to the secretagogue but guinea …

Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.

KC Flint, KB Leung, BN Hudspith, J Brostoff… - Br Med J (Clin Res …, 1985 - bmj.com
Bronchoalveolar lavage performed in 10 patients with extrinsic asthma and 14 controls
yielded similar recoveries of fluid and cells. Mast cells and eosinophils, however, formed a …

On the heterogeneity of mast cells

FL Pearce - Pharmacology, 1986 - karger.com
Current Review On the Heterogeneity of Mast Cells' Page 1 Current Review ©1986 S. Karger
AG. Basel Pharmacology 32: 61-71 (1986) 0031-70I2/86/0322-006IS2.75/0 On the …

Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells.

FL Pearce, AD Befus, J Gauldie… - Journal of immunology …, 1982 - journals.aai.org
Functional mast cells have been isolated from the lamina propria of the small intestine of rats
infected with the nematode Nippostrongylus brasiliensis. The cells released histamine on …

The purification and characterisation of hyaluronidase from the venom of the honey bee, Apis mellifera

DM Kemeny, N Dalton, AJ Lawrence… - European journal of …, 1984 - Wiley Online Library
Hyaluronidase has been purified from the venom of the honey bee, Apis mellifera. The
purification proved remarkably difficult, requiring a large number of chromatographic steps …