Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …

Maternal vitamin D insufficiency is associated with childhood rickets and longer-term
problems including schizophrenia and type 1 diabetes. Whilst maternal vitamin D …

Central nervous system involvement in multiple myeloma is a rare complication but carries a
very poor prognosis. We provide a review of current literature, including presentation …

Molecular markers like IgVH mutational status, chromosomal abnormalities, and CD38 and
ZAP-70 expression have prognostic value in B-cell chronic lymphocytic leukemia (B-CLL) …

Covid-19 endangers lives, has disrupted normal life, changed the way medicine is practised
and is likely to alter our world for the foreseeable future. Almost two years on since the …

Background: In many countries, current recommendations are that women take a daily 400-
μg folic acid supplement from before conception until the end of the 12th week of gestation …

Background: PCR detects clonal rearrangements of the Ig gene in lymphoproliferative
disorders. False negativity occurs in germinal centre/post-germinal centre lymphomas …

Pregnancy is proposed to be a Th2 phenomenon, where Th2 cytokines inhibit Th1
responses to improve foetal survival. The importance of interleukin-10 (IL-10), an …

Aging is associated with alterations in the immune system, effects which may be
exacerbated by inadequate zinc (Zn) status. We examined the relationship between Zn …

Two P-glycoprotein (P-gp) genes, MDR-1 (ABCB1) and MDR-3 (ABCB4), have been
identified in humans. This study was designed to investigate whether associations exist …