Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilising fine needle aspirate smears

G Lithwick-Yanai, N Dromi, A Shtabsky… - Journal of clinical …, 2017 - jcp.bmj.com
Aims The distinction between benign and malignant thyroid nodules has important
therapeutic implications. Our objective was to develop an assay that could classify …

[PDF][PDF] Spatiotemporal proteomic analysis of stress granule disassembly using APEX reveals regulation by SUMOylation and links to ALS pathogenesis

H Marmor-Kollet, A Siany, N Kedersha, N Knafo… - Molecular cell, 2020 - cell.com
Stress granules (SGs) are cytoplasmic assemblies of proteins and non-translating mRNAs.
Whereas much has been learned about SG formation, a major gap remains in …

Whole-genome sequencing reveals that variants in the interleukin 18 receptor accessory protein 3′ UTR protect against ALS

C Eitan, A Siany, E Barkan, T Olender, KR van Eijk… - Nature …, 2022 - nature.com
The noncoding genome is substantially larger than the protein-coding genome but has been
largely unexplored by genetic association studies. Here, we performed region-based rare …

BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures

YM Danino, L Molitor… - Nucleic Acids …, 2023 - academic.oup.com
Bloom's syndrome (BLM) protein is a known nuclear helicase that is able to unwind DNA
secondary structures such as G-quadruplexes (G4s). However, its role in the regulation of …

Differential expression of microRNA in serum fractions and association of Argonaute 1 microRNAs with heart failure

E Meiri, N Volinsky, N Dromi… - Journal of Cellular …, 2020 - Wiley Online Library
The serum or plasma microRNA (miRNA) molecules have been suggested as diagnostic
and prognostic biomarkers, in various pathological conditions. However, these molecules …

Non-coding genetic analysis implicates interleukin 18 receptor accessory protein 3′ UTR in amyotrophic lateral sclerosis

C Eitan, A Siany, E Barkan, T Olender, KR van Eijk… - bioRxiv, 2021 - biorxiv.org
The non-coding genome is substantially larger than the protein-coding genome, but the lack
of appropriate methodologies for identifying functional variants limits genetic association …

A nuclear role for ARGONAUTE-2 in regulation of neuronal alternative polyadenylation

R Ravid, A Siany, N Rivkin, C Eitan, H Marmor-Kollet… - BioRxiv, 2020 - biorxiv.org
Abstract Argonaute 2 (AGO2), the effector protein partner of microRNAs (miRNAs) in the
cytoplasmic RNA induced silencing complex, is further involved in nuclear RNA processing …

[PDF][PDF] 2HQ, UK.

H Marmor-Kollet, A Siany, N Kedersha, N Knafo… - researchgate.net
Cytoplasmic stress granules (SG) form in response to a variety of cellular stresses by phase-
separation of proteins associated with non-translating mRNAs. SG provide insight into the …

CLINICAL AND ANALYTICAL VALIDATION OF ROSETTAGX REVEALTM-A MICRORNA-BASED DIAGNOSTIC TEST FOR CLASSIFICATION OF THYROID …

M Leon, S Vorobyov, A Kulysh, M Hajdúch… - Endocrine …, 2016 - search.proquest.com
Abstract# 1201 Objective: The distinction between benign and malignant thyroid nodules
has important therapeutic implications. Many thyroid nodules are cytologically classified as …

[CITATION][C] Abstract# 1201: Clinical and Analytical Validation of Rosettagx Revealtm–A Microrna-Based Diagnostic Test for Classification of Thyroid Nodules

H Benjamin, GL Yanai, M Leon, A Shtabsky, A Zubkov… - Endocrine Practice, 2016 - Elsevier