Recent advances in whole‐slide imaging (WSI) technology have led to the development of a
myriad of computer vision and artificial intelligence‐based diagnostic, prognostic, and …

Aim: To demonstrate that MSI-WES is an accurate testing method for microsatellite instability
(MSI). Materials & methods: Microsatellite-based indels were counted in the variant call …

Currently, short DNA segments of sub-100 bp can be sequenced either directly by next-
generation sequencing and pyrosequencing, which are expensive, or indirectly, via Sanger …

Ku 70/80 is a regulator of the Non-Homologous End Joining (NHEJ) roles in
clinicopathological features, and has prognostic significance in breast cancer (BC) in …

Objective. The osteoporosis in thyroid disorder has the lowest report especially in sub-
Saharan Africa. This study aims to determine the prevalence, predictive factors, and …

Aims We previously described the quick multiplex consensus PCR (QMC-PCR) as a method
for rapid mutation screening in low-quality template. QMC-PCR has two-stages: a …

Introduction Microsatellite stable sporadic colorectal cancers (CRCs) can be classified as
either tumours with chromosomal instability (CIN+) or tumours that are 'Microsatellite and …

of the association is weak but supports published data. The negative association we
observed of PIK3CA mutation with BRAF mutation suggests that there is no generic co …

Aims Gene dosage can have a major impact on cell biology, although, hitherto, it has been
difficult to study using in vitro models. We sought to refine and accelerate the development of …

High-resolution melt analysis (HRMA) is a cheap and reliable post-polymerase chain
reaction (PCR) cancer mutation screening technique, which is fast gaining clinical …