Autoimmune hepatitis (AIH) with acute presentation is widely recognized as a distinct clinical
entity, and its clinicopathology has been extensively studied. In most cases, AIH with acute …

Biliary epithelial cells preferentially respond to various insults under chronic pathological
conditions leading to reactively atypical changes, hyperplasia, or the development of biliary …

Aims Although liver biopsy is crucial to diagnose and guide treatment decisions, a detailed
histological analysis of autoimmune hepatitis (AIH) with clinically acute presentations has …

Background Autoimmune hepatitis (AIH) is characterized by progressive inflammation and
necrosis of hepatocytes and eventually leads to a variety of phenotypes, including acute …

Aims Mass‐forming intrahepatic cholangiocarcinomas (MF‐iCCAs), involving small bile
ducts, bile ductules or canals of Hering, remain treated as a single entity. We aimed to …

Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to
hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined …

Aim Presently, no standardized definition or acceptable diagnostic criteria have been
established for acute presentation of autoimmune hepatitis (AP‐AIH), making it difficult to …

Immune-related adverse events (irAE) has been clarified according the usage of immune
checkpoint inhibitors (ICI). We primarily found indoleamine 2, 3-dioxygenase 1 (IDO-1) as a …

A well-documented Achilles heel of current cancer immunotherapy approaches is T cell
exhaustion within solid tumor tissues. The proinflammatory cytokine interleukin (IL)-23 has …

The biliary tract cancer (BTC) covers a range of carcinomas, including intrahepatic
cholangiocarcinoma (ICC), cholangiolocellular carcinoma (CoCC), perihilar …