User profiles for "author:Hong Kai Lee"

Hong Kai Lee

Agency for Science, Technology and Research
Verified email at immunol.a-star.edu.sg
Cited by 1583

[HTML][HTML] Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance

JW Tang, TT Lam, H Zaraket, WI Lipkin… - The Lancet Infectious …, 2017 - thelancet.com
Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include
respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human …

A diagnostic polymerase chain reaction assay for Zika virus

MND Balm, CK Lee, HK Lee, L Chiu… - Journal of medical …, 2012 - Wiley Online Library
Zika virus (ZIKV) is a mosquito‐borne flavivirus. Infection results in a dengue‐like illness with
fever, headache, malaise, and a maculopapular rash. Nearly all cases are mild and self …

[PDF][PDF] Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

Y Cheng, B Gunasegaran, HD Singh, CA Dutertre… - Immunity, 2021 - cell.com
Hepatocellular carcinoma (HCC) often develops following chronic hepatitis B virus (HBV)
infection and responds poorly to immune checkpoint blockade. Here, we examined the …

[HTML][HTML] Unsupervised spatially embedded deep representation of spatial transcriptomics

H Xu, H Fu, Y Long, KS Ang, R Sethi, K Chong, M Li… - Genome Medicine, 2024 - Springer
Optimal integration of transcriptomics data and associated spatial information is essential
towards fully exploiting spatial transcriptomics to dissect tissue heterogeneity and map out …

[HTML][HTML] Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma

S Chuah, J Lee, Y Song, HD Kim, M Wasser… - Journal of …, 2022 - Elsevier
Background & Aims While immune checkpoint blockade (ICB) has shown promise in
patients with hepatocellular carcinoma (HCC), it is associated with modest response rates …

Association between meteorological variations and activities of influenza A and B across different climate zones: a multi-region modelling analysis across the globe

KC Chong, TC Lee, S Bialasiewicz, J Chen, DW Smith… - Journal of Infection, 2020 - Elsevier
Objective To elucidate the effects of meteorological variations on the activity of influenza A
and B in 11 sites across different climate regions. Methods Daily numbers of laboratory …

Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity

RK Virk, J Jayakumar, IH Mendenhall… - Proceedings of the …, 2020 - National Acad Sciences
Influenza B viruses have circulated in humans for over 80 y, causing a significant disease
burden. Two antigenically distinct lineages (“B/Victoria/2/87-like” and “B/Yamagata/16/88 …

Comparative global epidemiology of influenza, respiratory syncytial and parainfluenza viruses, 2010–2015

TT Lam, JW Tang, FY Lai, H Zaraket, G Dbaibo… - Journal of Infection, 2019 - Elsevier
Objectives To improve our understanding of the global epidemiology of common respiratory
viruses by analysing their contemporaneous incidence at multiple sites. Methods 2010 …

Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology

E Kvedaraite, P Milne, A Khalilnezhad, M Chevrier… - Science …, 2022 - science.org
Langerhans cell histiocytosis (LCH) is a potentially fatal neoplasm characterized by the
aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein …

Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair

J Matsuo, D Douchi, K Myint, NN Mon, A Yamamura… - Gut, 2021 - gut.bmj.com
Objective Tissue stem cells are central regulators of organ homoeostasis. We looked for a
protein that is exclusively expressed and functionally involved in stem cell activity in rapidly …