User profiles for "author:Hong Kai Lee"
Hong Kai LeeAgency for Science, Technology and Research Verified email at immunol.a-star.edu.sg Cited by 1583 |
[HTML][HTML] Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance
Together with influenza, the non-influenza RNA respiratory viruses (NIRVs), which include
respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human …
respiratory syncytial virus, parainfluenza viruses, coronavirus, rhinovirus, and human …
A diagnostic polymerase chain reaction assay for Zika virus
Zika virus (ZIKV) is a mosquito‐borne flavivirus. Infection results in a dengue‐like illness with
fever, headache, malaise, and a maculopapular rash. Nearly all cases are mild and self …
fever, headache, malaise, and a maculopapular rash. Nearly all cases are mild and self …
[PDF][PDF] Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) often develops following chronic hepatitis B virus (HBV)
infection and responds poorly to immune checkpoint blockade. Here, we examined the …
infection and responds poorly to immune checkpoint blockade. Here, we examined the …
[HTML][HTML] Unsupervised spatially embedded deep representation of spatial transcriptomics
Optimal integration of transcriptomics data and associated spatial information is essential
towards fully exploiting spatial transcriptomics to dissect tissue heterogeneity and map out …
towards fully exploiting spatial transcriptomics to dissect tissue heterogeneity and map out …
[HTML][HTML] Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma
Background & Aims While immune checkpoint blockade (ICB) has shown promise in
patients with hepatocellular carcinoma (HCC), it is associated with modest response rates …
patients with hepatocellular carcinoma (HCC), it is associated with modest response rates …
Association between meteorological variations and activities of influenza A and B across different climate zones: a multi-region modelling analysis across the globe
Objective To elucidate the effects of meteorological variations on the activity of influenza A
and B in 11 sites across different climate regions. Methods Daily numbers of laboratory …
and B in 11 sites across different climate regions. Methods Daily numbers of laboratory …
Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity
RK Virk, J Jayakumar, IH Mendenhall… - Proceedings of the …, 2020 - National Acad Sciences
Influenza B viruses have circulated in humans for over 80 y, causing a significant disease
burden. Two antigenically distinct lineages (“B/Victoria/2/87-like” and “B/Yamagata/16/88 …
burden. Two antigenically distinct lineages (“B/Victoria/2/87-like” and “B/Yamagata/16/88 …
Comparative global epidemiology of influenza, respiratory syncytial and parainfluenza viruses, 2010–2015
Objectives To improve our understanding of the global epidemiology of common respiratory
viruses by analysing their contemporaneous incidence at multiple sites. Methods 2010 …
viruses by analysing their contemporaneous incidence at multiple sites. Methods 2010 …
Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology
Langerhans cell histiocytosis (LCH) is a potentially fatal neoplasm characterized by the
aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein …
aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein …
Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair
J Matsuo, D Douchi, K Myint, NN Mon, A Yamamura… - Gut, 2021 - gut.bmj.com
Objective Tissue stem cells are central regulators of organ homoeostasis. We looked for a
protein that is exclusively expressed and functionally involved in stem cell activity in rapidly …
protein that is exclusively expressed and functionally involved in stem cell activity in rapidly …