The molecular genetics and morphometry‐based endometrial intraepithelial neoplasia classification system predicts disease progression in endometrial hyperplasia …

JP Baak, GL Mutter, S Robboy… - … Journal of the …, 2005 - Wiley Online Library
BACKGROUND The objective of this study was to compare the accuracy of disease
progression prediction of the molecular genetics and morphometry‐based Endometrial …

MicroRNA gene expression deregulation in human breast cancer

MV Iorio, M Ferracin, CG Liu, A Veronese, R Spizzo… - Cancer research, 2005 - AACR
MicroRNAs (miRNAs) are a class of small noncoding RNAs that control gene expression by
targeting mRNAs and triggering either translation repression or RNA degradation. Their …

[HTML][HTML] Supervised risk predictor of breast cancer based on intrinsic subtypes

JS Parker, M Mullins, MCU Cheang… - Journal of clinical …, 2009 - ncbi.nlm.nih.gov
Purpose To improve on current standards for breast cancer prognosis and prediction of
chemotherapy benefit by developing a risk model that incorporates the gene expression …

[HTML][HTML] The molecular portraits of breast tumors are conserved across microarray platforms

Z Hu, C Fan, DS Oh, JS Marron, X He, BF Qaqish… - BMC genomics, 2006 - Springer
Background Validation of a novel gene expression signature in independent data sets is a
critical step in the development of a clinically useful test for cancer patient risk-stratification …

[HTML][HTML] Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

JI Herschkowitz, K Simin, VJ Weigman, I Mikaelian… - Genome biology, 2007 - Springer
Background Although numerous mouse models of breast carcinomas have been developed,
we do not know the extent to which any faithfully represent clinically significant human …

An audit of endoscopic complications in adult eosinophilic esophagitis

MS Cohen, AB Kaufman, JP Palazzo, D Nevin… - Clinical …, 2007 - Elsevier
Background & Aims: Eosinophilic esophagitis (EoE) in adults, characterized by the triad of
dysphagia, a ringed esophagus, and mucosal eosinophilic infiltration, has associated …

[HTML][HTML] The FHIT gene, spanning the chromosome 3p14. 2 fragile site and renal carcinoma–associated t (3; 8) breakpoint, is abnormal in digestive tract cancers

M Ohta, H Inoue, MG Cotticelli, K Kastury, R Baffa… - Cell, 1996 - cell.com
A 200–300 kb region of chromosome 3p14. 2, including the fragile site locus FRA3B, is
homozygously deleted in multiple tumor-derived cell lines. Exon amplification from cosmids …

PD-L1 status in breast cancer: current view and perspectives

S Vranic, FS Cyprian, Z Gatalica, J Palazzo - Seminars in cancer biology, 2021 - Elsevier
Breast cancer was traditionally not considered a particularly immunogenic tumor. However,
recent developments have shown that some aggressive triple-negative breast cancers are …

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

BT Hennessy, AM Gonzalez-Angulo, K Stemke-Hale… - Cancer research, 2009 - AACR
Metaplastic breast cancers (MBC) are aggressive, chemoresistant tumors characterized by
lineage plasticity. To advance understanding of their pathogenesis and relatedness to other …

MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets

R Baffa, M Fassan, S Volinia, B O'Hara… - The Journal of …, 2009 - Wiley Online Library
Small non‐coding microRNAs (miRNAs) contribute to cancer development and progression,
and are differentially expressed in normal tissues and cancers. However, the specific role of …