Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is an organ-
specific autoimmune disease that predominantly affects middle-aged women and is …

In recent years, the pathology and pathogenesis of bile duct loss have been extensively
studied, and a num-ber of hepatobiliary diseases have been added to the list of ductopenic …

Idiopathic portal hypertension (IPH) is characterized by a long-standing presinusoidal portal
hypertension of unknown etiology in adults. Some unidentified agent (s) affect (s) the …

OBJECTIVE To characterize the phenotypic changes of adipose tissue macrophages
(ATMs) under different conditions of insulin sensitivity. RESEARCH DESIGN AND …

Sclerosing cholangitis (SC) is a heterogeneous disease entity. Different etiologies such as
choledocholithiasis, biliary tumor, or pericholangitis can manifest as SC. Hepatic …

Background: Gastric carcinoma is still a major leading cause of cancer death in East Asia.
Since angiogenesis is a necessary condition for invasion and metastasis, its regulation is of …

Chronic sclerosing sialadenitis (CSS) is a cryptogenic tumor-like condition of the salivary
gland (s). While immune-mediated processes are suspected in its pathogenesis, and CSS is …

Abstract CD4+ CD25high regulatory T cells (Tregs) play a critical role in self‐tolerance, as
seen in murine autoimmunity. Studies on Tregs in human autoimmunity have focused …

IL-5 is involved in a number of immune responses such as helminth infection and allergy. IL-
5 also plays roles in innate immunity by maintaining B-1 B cells and mucosal IgA production …

Diabetic nephropathy is a major microvascular complication in long-standing diabetic
patients who eventually undergo renal dialysis or transplantation. To prevent development …