User profiles for "author:Kok-Siong Poon"
 | Kok Siong PoonNational University Health System (NUHS) Verified email at nuhs.edu.sg Cited by 218 |
LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function
KE Waddington, GA Robinson… - Proceedings of the …, 2021 - National Acad Sciences
The liver X receptor (LXR) is a key transcriptional regulator of cholesterol, fatty acid, and
phospholipid metabolism. Dynamic remodeling of immunometabolic pathways, including …
phospholipid metabolism. Dynamic remodeling of immunometabolic pathways, including …
Production of artificial seeds derived from encapsulated in vitro micro shoots of cauliflower, Brassica oleracea var. botrytis
A high number of micro shoots (21+/-2.31) of Brassica oleracea var. botrytis (cauliflower)
were obtained when hypocotyl explants from 2-week-old aseptic seedlings were cultured on …
were obtained when hypocotyl explants from 2-week-old aseptic seedlings were cultured on …
Challenges in molecular diagnosis of Wilson disease: viewpoint from the clinical laboratory
KS Poon, ZH Teo, JH Yap, ESC Koay… - Journal of Clinical …, 2020 - jcp.bmj.com
Wilson disease (WD), a disorder of copper metabolism resulting in copper accumulation in
the liver and other organs, is an inherited autosomal recessive genetic condition. 1 …
the liver and other organs, is an inherited autosomal recessive genetic condition. 1 …
[HTML][HTML] In silico analysis of BRCA1 and BRCA2 missense variants and the relevance in molecular genetic testing
KS Poon - Scientific Reports, 2021 - nature.com
Over the years since the genetic testing of BRCA1 and BRCA2 has been conducted for
research and later introduced into clinical practice, a high number of missense variants have …
research and later introduced into clinical practice, a high number of missense variants have …
[HTML][HTML] Dynamic altruistic cooperation within breast tumors
MSB Masroni, KW Lee, VKM Lee, SB Ng, CT Law… - Molecular Cancer, 2023 - Springer
Background Social behaviors such as altruism, where one self-sacrifices for collective
benefits, critically influence an organism's survival and responses to the environment. Such …
benefits, critically influence an organism's survival and responses to the environment. Such …
Somatic embryogenesis and plant regeneration from hypocotyl and leaf explants of Brassica oleracea var. botrytis (cauliflower)
We investigated direct and indirect formation of somatic embryogenesis in Brassica oleracea
var. botrytis (cauliflower), a very important vegetable crop worldwide. Direct somatic …
var. botrytis (cauliflower), a very important vegetable crop worldwide. Direct somatic …
Targeted next-generation sequencing of the ATP7B gene for molecular diagnosis of Wilson disease
Objectives In recent years, next-generation sequencing (NGS) technologies, which enable
high throughput sample processing at relatively lower costs, are adopted in both research …
high throughput sample processing at relatively lower costs, are adopted in both research …
Multicenter study on the genetics of glomerular diseases among southeast and south Asians: Deciphering Diversities‐Renal Asian Genetics Network (DRAGoN)
L Lu, YC Yap, DQ Nguyen, YH Chan, JL Ng… - Clinical …, 2022 - Wiley Online Library
Multinational studies have reported monogenic etiologies in 25%–30% of children with
steroid‐resistant nephrotic syndrome. Such large studies are lacking in Asia. We established …
steroid‐resistant nephrotic syndrome. Such large studies are lacking in Asia. We established …
Caveats of reporting cycle threshold values from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) qualitative polymerase chain reaction assays: a …
KS Poon, N Wen-Sim Tee - Clinical Infectious Diseases, 2021 - academic.oup.com
Figure 1. CDI incidence for intervention (OVP) and control groups of Johnson et al [1] as
incidence rate per 10 000 patient days, versus published US CDI benchmarks of 7.3 [3] and …
incidence rate per 10 000 patient days, versus published US CDI benchmarks of 7.3 [3] and …
Validation of the Hemochromatosis (2SNP+) Direct EUROArray Assay for the Molecular Diagnosis of HFE-Related Hereditary Hemochromatosis
Aim: Two missense variants in the HFE gene, c. 845G> A (p. Cys282Tyr) and c. 187C> G (p.
His63Asp), are commonly screened as part of the diagnostic workup for HFE-related …
His63Asp), are commonly screened as part of the diagnostic workup for HFE-related …