Sarcoma of the breast: an update on a rare entity

SZ Lim, KW Ong, BKT Tan, S Selvarajan… - Journal of clinical …, 2016 - jcp.bmj.com
Breast sarcoma is a rare condition. It consists of a heterogeneous group of non-epithelial
tumours arising from the mesenchymal tissue of the breast. It has a distinctly different natural …

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma

WK Lim, CK Ong, J Tan, AA Thike, CCY Ng… - Nature …, 2014 - nature.com
Fibroadenomas are the most common breast tumors in women under 30 (refs.,). Exome
sequencing of eight fibroadenomas with matching whole-blood samples revealed recurrent …

Genomic landscapes of breast fibroepithelial tumors

J Tan, CK Ong, WK Lim, CCY Ng, AA Thike, LM Ng… - Nature …, 2015 - nature.com
Breast fibroepithelial tumors comprise a heterogeneous spectrum of pathological entities,
from benign fibroadenomas to malignant phyllodes tumors. Although MED12 mutations …

Photodynamic-therapy-activated immune response against distant untreated tumours in recurrent angiosarcoma

PSP Thong, KW Ong, NSG Goh, KW Kho… - The lancet …, 2007 - thelancet.com
We report the case of a 64-year-old Chinese man with histologically proven multifocal
angiosarcoma of the head and neck. To our knowledge, this was the first clinical case in …

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

SY Loo, LP Toh, WH Xie, E Pathak, W Tan, S Ma… - Science …, 2021 - science.org
Cell state transitions control the functional behavior of cancer cells. Epithelial-to-
mesenchymal transition (EMT) confers cancer stem cell-like properties, enhanced …

Expression of EBV latent antigens, mammalian target of rapamycin, and tumor suppression genes in EBV-positive smooth muscle tumors: clinical and therapeutic …

KW Ong, M Teo, V Lee, D Ong, A Lee, CS Tan… - Clinical Cancer …, 2009 - AACR
Purpose: EBV-positive smooth muscle tumor (EBV+ SMT) is a rare disease with no
established therapy. We describe the largest single institution analysis in renal transplant …

False negative rate for intraoperative sentinel lymph node frozen section in patients with breast cancer: a retrospective analysis of patients in a single Asian institution

J Wong, WS Yong, AA Thike, J Iqbal… - Journal of Clinical …, 2015 - jcp.bmj.com
Background and objective Intraoperative frozen section of the sentinel lymph node (SLN) in
clinically node negative breast cancer patients detects metastatic disease and enables …

Genomic characterisation of breast fibroepithelial lesions in an international cohort

ND Md Nasir, CCY Ng, V Rajasegaran… - The Journal of …, 2019 - Wiley Online Library
Fibroepithelial lesions (FELs) are a heterogeneous group of tumours comprising
fibroadenomas (FAs) and phyllodes tumours (PTs). Here we used a 16‐gene panel that was …

[HTML][HTML] Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing

CCY Ng, NDM Nasir, BN Loke, TKY Tay, AA Thike… - Modern Pathology, 2021 - Elsevier
Breast fibroepithelial lesions are biphasic tumors which comprise the common benign
fibroadenomas (FAs) and the rarer phyllodes tumors (PTs). This study analyzed 262 (42%) …

[HTML][HTML] A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions

Y Sim, GXP Ng, CCY Ng, V Rajasegaran… - BMC Medical …, 2019 - Springer
Background Known collectively as breast fibroepithelial lesions (FELs), the common
fibroadenomas (FAs) and the rarer phyllodes tumors (PTs) are a heterogenous group of …