Activation and adoptive transfer of Epstein–Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease
The treatment of Epstein–Barr virus (EBV)-associated lymphoproliferative disease (PTLD) in
EBV seronegative solid organ transplant recipients who acquire their EBV infection after …
EBV seronegative solid organ transplant recipients who acquire their EBV infection after …
Phase I Trial of a CD8+ T-Cell Peptide Epitope-Based Vaccine for Infectious Mononucleosis
SL Elliott, A Suhrbier, JJ Miles, G Lawrence… - Journal of …, 2008 - Am Soc Microbiol
ABSTRACT A single blind, randomized, placebo-controlled, single-center phase I clinical
trial of a CD8+ T-cell peptide epitope vaccine against infectious mononucleosis was …
trial of a CD8+ T-cell peptide epitope vaccine against infectious mononucleosis was …
Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine
MGE O'Rourke, M Johnson, C Lanagan, J See… - Cancer immunology …, 2003 - Springer
Advanced metastatic melanoma is incurable by standard treatments, but occasionally
responds to immunotherapy. Recent trials using dendritic cells (DC) as a cellular adjuvant …
responds to immunotherapy. Recent trials using dendritic cells (DC) as a cellular adjuvant …
Asymptomatic primary Epstein-Barr virus infection occurs in the absence of blood T-cell repertoire perturbations despite high levels of systemic viral load
SL Silins, MA Sherritt, JM Silleri… - Blood, The Journal …, 2001 - ashpublications.org
Primary infection with the human herpesvirus, Epstein-Barr virus (EBV), may result in
subclinical seroconversion or may appear as infectious mononucleosis (IM), a …
subclinical seroconversion or may appear as infectious mononucleosis (IM), a …
Delivery of multiple CD8 cytotoxic T cell epitopes by DNA vaccination
SA Thomson, MA Sherritt, J Medveczky… - The Journal of …, 1998 - journals.aai.org
Abstract Development of CD8 αβ CTL epitope-based vaccines requires an effective strategy
capable of co-delivering large numbers of CTL epitopes. Here we describe a DNA plasmid …
capable of co-delivering large numbers of CTL epitopes. Here we describe a DNA plasmid …
Recombinant polyepitope vaccines for the delivery of multiple CD8 cytotoxic T cell epitopes.
SA Thomson, SL Elliott, MA Sherritt… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
Abstract Development of epitope-based CD8 alpha beta CTL vaccines requires effective
strategies for codelivery of large numbers of individual epitopes. We have designed an …
strategies for codelivery of large numbers of individual epitopes. We have designed an …
Reconstitution of the latent T-lymphocyte response to Epstein-Barr virus is coincident with long-term recovery from posttransplant lymphoma after adoptive …
MA Sherritt, M Bharadwaj, JM Burrows… - …, 2003 - journals.lww.com
Background. Adoptive transfer of Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes
(CTLs) has been used to treat EBV-induced posttransplant lymphoproliferative disease …
(CTLs) has been used to treat EBV-induced posttransplant lymphoproliferative disease …
An HLA-A2 polyepitope vaccine for melanoma immunotherapy
L Mateo, J Gardner, Q Chen, C Schmidt… - The Journal of …, 1999 - journals.aai.org
Epitope-based vaccination strategies designed to induce tumor-specific CD8 CTL are being
widely considered for cancer immunotherapy. Here we describe a recombinant poxvirus …
widely considered for cancer immunotherapy. Here we describe a recombinant poxvirus …
A single-dose combination study with the experimental antimalarials artefenomel and DSM265 to determine safety and antimalarial activity against blood-stage …
JS McCarthy, T Rückle, SL Elliott… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
Artefenomel and DSM265 are two new compounds that have been shown to be well
tolerated and effective when administered as monotherapy malaria treatment. This study …
tolerated and effective when administered as monotherapy malaria treatment. This study …
Crossreactive recognition of viral, self, and bacterial peptide ligands by human class I-restricted cytotoxic T lymphocyte clonotypes: implications for molecular mimicry …
IS Misko, SM Cross, R Khanna… - Proceedings of the …, 1999 - National Acad Sciences
The immunodominant, CD8+ cytotoxic T lymphocyte (CTL) response to the HLA-B8-
restricted peptide, RAKFKQLL, located in the Epstein–Barr virus immediate-early antigen …
restricted peptide, RAKFKQLL, located in the Epstein–Barr virus immediate-early antigen …