Glycated haemoglobin (HbA1c) monitoring

TM Reynolds, WSA Smellie, PJ Twomey - Bmj, 2006 - bmj.com
Glycated haemoglobin (HbA1c) monitoring | The BMJ Skip to main content Intended for
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Relationship between serum copper, ceruloplasmin, and non–ceruloplasmin-bound copper in routine clinical practice

PJ Twomey, A Viljoen, IM House… - Clinical …, 2005 - academic.oup.com
Copper is an essential cofactor for many enzymes, including cytochromes, but it is toxic in its
unbound form. The vast majority of serum copper is transported bound to ceruloplasmin; the …

Pro‐protein subtilisin kexin‐9 (PCSK 9) inhibition in practice: lipid clinic experience in 2 contrasting UK centres

M Kohli, K Patel, Z MacMahon… - … journal of clinical …, 2017 - Wiley Online Library
Background Prescribing criteria have been suggested for proprotein convertase subtilisin
kexin‐9 (PCSK‐9) inhibitors but few studies exist of their real‐world effectiveness. Methods …

Non-ceruloplasmin-bound copper in routine clinical practice in different laboratories

PJ Twomey, A Viljoen, TM Reynolds… - Journal of Trace …, 2008 - Elsevier
BACKGROUND: Copper is an essential nutrient but is toxic when the free form is in excess.
Wilson's disease (WD) is an autosomal recessive disorder of copper excess. Its diagnosis is …

All MoMs are not equal: some statistical properties associated with reporting results in the form of multiples of the median.

JC Bishop, FD Dunstan, BJ Nix… - American journal of …, 1993 - ncbi.nlm.nih.gov
The statistical procedure for discriminating between a Down syndrome or neural tube defect
(NTD) fetus and a normal fetus relies, to a great extent, on the reporting of maternal serum …

Genetic risk scores in lipid disorders

AS Wierzbicki, TM Reynolds - Current Opinion in Cardiology, 2019 - journals.lww.com
Genetic risk scores in lipid disorders : Current Opinion in Cardiology Genetic risk scores in lipid
disorders : Current Opinion in Cardiology Log in or Register Subscribe to journalSubscribe Get …

Accuracy of cardiovascular risk estimation for primary prevention in patients without diabetes

TM Reynolds, P Twomey… - … of cardiovascular risk, 2002 - journals.sagepub.com
Background The burden of atherosclerosis has led to treatment prioritization on high-risk
individuals without established cardiovascular disease based on risk estimates. We …

Copper: caeruloplasmin ratio

PJ Twomey, A Viljoen, IM House… - Journal of clinical …, 2007 - jcp.bmj.com
Investigation of copper status can be a diagnostic challenge. The non-caeruloplasmin-
bound copper (NCC) has deficiencies; accordingly, the copper: caeruloplasmin ratio has …

Usefulness of Orlistat in the treatment of severe hypertriglyceridemia

AS Wierzbicki, TM Reynolds, MA Crook - American Journal of …, 2002 - ajconline.org
Type V hyperlipidemia is distinguished by gross hypertriglyceridemia (1,770 mg/dl [20
mmol/L]) and the presence of high concentrations of chylomicrons, very-low density …

A comparison of algorithms for initiation of lipid lowering therapy in primary prevention of coronary heart disease

AS Wierzbicki, TM Reynolds, K Gill… - Journal of …, 2000 - journals.sagepub.com
Objective To compare nine different algorithms for determining the necessity for drug
treatment of hyperlipidaemia in patients without cardiovascular disease. Design Risk-factor …