Despite the ongoing development of automated hematology analyzers to optimize complete
blood count results, platelet count still suffers from pre-analytical or analytical pitfalls …

We analyzed prognostic factors of response, response duration, and possible impact on
survival of epoetin α, epoetin β, or darbepoetin α (DAR) with or without granulocyte colony …

Cancer cells require nutrients and energy to adapt to increased biosynthetic activity, and
protein synthesis inhibition downstream of mammalian target of rapamycin complex 1 …

The phosphatidylinositol 3-kinase (PI3K)/Akt and mTORC1 pathways are frequently
activated, representing potential therapeutic targets in acute myeloid leukemia (AML). In 19 …

Chronic myelomonocytic leukemia (CMML) is a myelodysplastic syndrome/
myeloproliferative neoplasm whose diagnosis is currently based on the elevation of …

Abstract The phosphoinositide 3-kinase (PI3K/Akt) pathway is activated in acute
myelogenous leukemia (AML) and is promising for targeted inhibition. Ninety-two patients …

Receptor or nonreceptor tyrosine kinases (TKs) are known to play an important role in
leukemogenesis. Here we studied the level of protein tyrosine phosphorylations in a series …

Background Alterations in the PI3K/Akt pathway are found in a wide range of cancers and
the development of PI3K inhibitors represents a promising approach to cancer therapy …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive leukemia for
which we developed a nationwide network to collect data from new cases diagnosed in …

Aims To determine full blood count (FBC) normal reference values for adults. Methods FBC
normal values for healthy adults were defined, after establishing preanalytical conditions, in …