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Antihaemophilic factor deficiency, capillary defect of von Willebrand type, and idiopathic thrombocytopenia occurring in one family
  1. E. K. Blackburn,
  2. J. M. Macfie,
  3. J. H. Monaghan,
  4. A. P. M. Page
  1. Department of Haematology, The Royal Infirmary and Hospital, Sheffield
  2. City and Children's Hospitals, Nottingham


    Thrombocytopenia of the type found in idiopathic thrombocytopenic purpura is described in a family with a deficiency of antihaemophilic factor, and a capillary abnormality. The propositus (father) has thrombocytopenia and abnormal platelet morphology, together with a plasma deficiency of antihaemophilic factor, but normal capillaries. His two daughters each are deficient in antihaemophilic factor with normal platelets but abnormal capillaries.

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