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Renal enlargement in chronic cor pulmonale
  1. P. A. Ellis
  1. Department of Pathology, Newcastle General Hospital


    Examination of the post-mortem records of 1,391 unselected cases showed that the commonest condition associated with excessive diffuse enlargement of the kidneys was chronic cor pulmonale. A less striking enlargement was found in some cases of chronic rheumatic heart disease.

    A hypothesis is put forward in which the renal enlargement is regarded as a work hypertrophy brought about by the kidneys' efforts to compensate for a chronic respiratory acidosis.

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