Article Text

Download PDFPDF
The total cellularity of the bone marrow in man
  1. W. J. Harrison
  1. Department of Haematology, Westminster Hospital, London 2

    Abstract

    The Fe59 method of Suit (1957) has been used to estimate total bone marrow cellularity in 10 haematologically normal patients. A mean figure of 10·4 × 109 nucleated cells/kg. body weight was obtained. Simultaneous estimates from marrow obtained by rib excision produced a mean value of 11·1 × 109 nucleated cells/kg.

    Previous work by this and other methods is reviewed. While some results agree well with those of the present work, one is higher by 50% and another by 300%. Corrections are suggested which reduce these figures and bring all published results within a small range.

    Reasonably accurate determinations of total marrow cellularity in disease will not be possible until more is known of marrow Fe59 uptake in abnormal states.

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Footnotes

    • 1 Based on a paper read at a meeting of the Association of Clinical Pathologists on 22 September 1961.

    • 2 Present address: Department of Morbid Anatomy, Westminster Hospital Medical School, London, S.W.1.