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A useful photometric test for the diagnosis of Von Willebrand's disease
  1. H. Vainer,
  2. J. P. Caen,
  3. D. Chatelain,
  4. H. Michel
  1. Institut de Recherches sur les Leucémies de la Faculté de Médecine, Paris
  2. Centre de Recherches sur les Leucémies de l'Association Claude Bernard, Hôpital Saint-Louis, Paris


    When small amounts of adenosine diphosphate are added to citrated platelet-rich plasma, the consequent modification of platelets leads to a decrease in optical density. In Von Willebrand's disease the optical density at 610 mμ increases instead of decreasing. This finding is used to study the effects of treatment on this disorder.

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