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A vertical diffusion method for the microbiological assay of isoniazid
  1. Janet Lloyd,
  2. D. A. Mitchison
  1. Medical Research Council's Unit for Research on Drug Sensitivity in Tuberculosis, Postgraduate Medical School of London


    A method is described for the assay of isoniazid in serum and other fluids by diffusion along slopes of Löwenstein-Jensen medium inoculated with tubercle bacilli. The method is convenient, rapid and robust, but is less accurate than diffusion systems for the assay of some other substances.

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