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Waldenström's macroglobulinaemia treated with cylophosphamide and chlorambucil
  1. R. M. Buckle,
  2. G. C. Jenkins,
  3. G. L. Mills
  1. St. Bartholomew's Hospital, London
  2. North Middlesex Hospital, London
  3. Courtauld Institute of Biochemistry, Middlesex Hospital, London


    A case of primary macroglobulinaemia of Waldenström is described in which prolonged treatment with the alkylating agents of cyclophosphamide and chlorambucil led to a sustained reduction in the concentration of circulating macroglobulin together with a concurrent improvement in the patient's symptoms.

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