Focal granulomatous giant cell reticulosis was observed in lymph nodes from treated cases of chronic lymphatic and chronic myeloid leukaemia. On the basis of clinical behaviour and histological appearance, it seems plausible that in the terminal phase of leukaemia non-neoplastic reactive reticulosis developed very similar in appearance to lymphogranulomatosis. The possible relationship between malignant lymph node tumours, Hodgkin's disease, and leukaemia is discussed. Repeated biopsies from leukaemic patients would perhaps permit of further clarification of this process.
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