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The histology and cytology of changes in the epithelium of the cervix uteri
  1. A. D. T. Govan,
  2. R. M. Haines,
  3. F. A. Langley,
  4. C. W. Taylor,
  5. A. S. Woodcock2
  1. Royal College of Obstetricians and Gynaecologists, London


    Abnormalities of the cervical epithelium are set out in two main groups: bland lesions which are regarded as unrelated to malignancy, and malign lesions which are considered as potential precursors of invasive carcinoma. The histological features of each condition and the cytological pattern of the corresponding cervical smear are described and correlated.

    Cone biopsy is advocated as the only satisfactory form of cervical biopsy for both the diagnosis and evaluation of lesions such as dysplasia and carcinoma in situ. It is emphasized that further study is necessary to determine their natural history and prognosis in relation to invasive carcinoma.

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    • 2 The authors of this report are the members of a panel appointed by the Royal College of Obstetricians and Gynaecologists.

    • 1 Copies of this paper may be obtained from the Publishing Manager, B.M.A. House, Tavistock Square, London, price 5s each, the envelope marked, Journal of Clinical Pathology, broadsheets.