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Agglutination of platelets by a serum factor in the presence of EDTA
  1. E. Gowland,
  2. H. E. M. Kay,
  3. Judy C. Spillman,
  4. J. R. Williamson
  1. Department of Clinical Pathology, Royal Marsden Hospital, London
  2. Chester Beatty Research Institute, Institute of Cancer Research, London


    The platelets of a patient with reticulum-cell sarcoma were found to exhibit agglutination and cytopathic changes when her blood was treated with EDTA but not with other anticoagulants. Investigation showed that the phenomenon was caused by a serum factor that was probably an antibody.

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