Article Text

Download PDFPDF
Precipitins with relevance to farmer's lung and aspergillosis in normal and other sera
  1. J. E. Jameson
  1. Public Health Laboratory, Brighton


    Immunodiffusion, immunoosmophoresis, and precipitin inhibition tests were carried out on various categories of sera with extracts of Micropolyspora faeni (Thermopolyspora polyspora), Aspergillus fumigatus, and Thermoactinomyces vulgaris. The sera were from clinical cases of farmer's lung, from symptomless farm workers, from expectant mothers, from tuberculous and from asthmatic patients, and from patients with miscellaneous lung disorders. The clinical cases of farmer's lung became divisible into two groups by serological tests for antibody to a particular soluble antigenic component of M. faeni. The suggestion is made that one of these two groups of cases may be aetiologically unrelated to M. faeni. One of six sera tested in this group reacted strongly with an extract of T. vulgaris. Antibodies to certain components of some extracts of M. faeni and of A. fumigatus were found in a high proportion of normal sera. Possible reasons for this finding have been given.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


    • 1 A report to the working party on farmer's lung of the Public Health Laboratory Service.