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Use of soluble swabs in the diagnosis of bladder neoplasia
  1. P. A. Trott,
  2. Grant Williams,
  3. P. W. Attridge
  1. Department of Pathology, Imperial Cancer Research Fund, London
  2. Institute of Urology, London


    A technique is described for obtaining samples of bladder epithelium using soluble swabs. Changes indicating neoplasia were seen in a large proportion of patients with bladder carcinoma. These changes were absent in the non-neoplastic control cases. The method provided tissue similar to that obtained by biopsy and surgical removal. The cellular appearances resembled those seen in neoplastic cells exfoliated into urine.

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