Article Text

Download PDFPDF
Studies on the 57Co vitamin B12 plasma level absorption test
  1. B. K. Armstrong,
  2. H. J. Woodliff
  1. Department of Haematology, Royal Perth Hospital, Perth, Western Australia


    Results of the 57Co vitamin B12 plasma level absorption test are described in 163 patients. The use of intramuscular carbachol with the test and the presence or absence of current vitamin B12 therapy did not affect the test results. Injection of 1,000 μg of unlabelled vitamin B12 during the test augmented plasma levels in patients with normal absorption but tests without this injection gave satisfactory differentiation between the normal and malabsorption ranges. Results from patients having had a gastrectomy, ileal resection, or a past history of adult coeliac disease are also described. Amongst patients with presumed Addisonian pernicious anaemia, two with unresolved equivocal results and three with falsely normal results were found. The significance of these is discussed.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.