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Thermal damage to red cells
  1. S. Baar,
  2. D. J. Arrowsmith
  1. Medical Research Council Industrial Injuries and Burns Unit, Birmingham Accident Hospital, and the University of Aston in Birmingham, Gosta Green, Birmingham


    Erythrocytes from a burned patient show a temporal sequence of morphological changes. Immediate severe changes occur which are followed by a transient phase only of less abnormal morphology.

    Heating whole blood in vitro to 49°C instead of 50°C does not show the expected dose response curve.

    Heating whole blood in vitro to 50°C induces progressive morphological changes.

    Fractionation of whole blood and subsequent heating to 48°C show the older cells to be less deformable.

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