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Multiple immunological abnormalities in a family
  1. Alastair M. S. Mason1,
  2. Peter L. Golding2
  1. Southampton General Hospital, London
  2. London Hospital, London


    The family of a woman with multiple autoimmune diseases has been investigated. Clinical evidence of an autoimmune disorder was detected in two relatives, and five others had serological and immunoglobulin abnormalities. It is suggested that there is an inherited predisposition to develop immunological abnormalities, and that a number of associated autoimmune diseases may develop in families in which this occurs.

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    • 1 Present address: Clinical Research Centre, Northwick Park Hospital, Harrow, Middlesex.

    • 2 Present address: The Division of Medicine, the London Hospital.