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Virucidal activity of chlorhexidine on strains of Herpesvirus hominis, poliovirus, and adenovirus
  1. Andrew Bailey,
  2. Maurice Longson
  1. Department of Bacteriology and Virology, University of Manchester


    The infectivity titre of two strains of Herpesvirus hominis was reduced by not more than six log10 units by 90 minutes' exposure to chlorhexidine at a final concentration of 0·02% at room temperature. Under identical conditions the compound was ineffective against a vaccine strain of poliovirus and against an adenovirus. Experimental conditions are described whereby the toxic effect of the disinfectant on the tissue culture assay systems are minimized.

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