Article Text

Download PDFPDF

Aggregation of human platelets by commercial preparations of bovine and porcine antihaemophilic globulin
  1. C. D. Forbes,
  2. R. D. Barr,
  3. G. P. McNicol,
  4. A. S. Douglas1
  1. University Department of Medicine, Glasgow Royal Infirmary


    Infusion of commercial preparations of porcine and bovine antihaemophilic globulin into three haemophilic patients produced transient thrombocytopenia. This platelet-aggregating activity has been shown to be present in a wide range of animal plasmas and is related to the fibrinogen fraction. The mechanism of platelet aggregation by animal fibrinogen is discussed and some inhibitors of the reaction are described.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


    • 1 Present address: Department of Medicine, University of Aberdeen. Foresterhill, Aberdeen AB9 2ZD.