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A `virus-free' cell line derived from a patient with infectious mononucleosis
  1. S. D. Marston,
  2. E. J. P. Almond,
  3. N. P. Bishun,
  4. E. D. Maunsell,
  5. R. N. P. Sutton
  1. Department of Medical Microbiology, King's College Hospital Medical School, London
  2. St Giles' Hospital, London
  3. Research Department, Marie Curie Memorial Foundation, Oxted, Surrey


    A continuous cell culture line, derived from a nurse with infectious mononucleosis, is described. Electron microscopic and immunofluorescent examination suggested that it was substantially free from detectable complete virus particles, although the presence of a soluble complement-fixing antigen showed the persistence of other antigenic components of the EB virus.

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