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Chromosome abnormalities in chronic active hepatitis
  1. D. T. Stefanescu,
  2. M. Moanga,
  3. M. Teodorescu,
  4. J. Brucher
  1. Dr Babeş Institute for Pathology and Medical Genetics, Bucharest
  2. Department of Internal Medicine, School of Medicine, Bucharest
  3. Dr Cantacuzino Institute, Bucharest


    An investigation on human peripheral blood lymphocyte chromosomes in chronic active hepatitis was carried out. A higher percentage of chromatid and chromosome lesions was recorded in all patients studied as compared with control groups—normal individuals, healthy subjects who had suffered from acute viral hepatitis, patients with alcoholic liver disease, and patients with mechanical jaundice due to cancer. The possible origin of these abnormalities is discussed.

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