Rapid diagnoses were made on 510 breast lumps by three methods in sequence and the results compared with those obtained by paraffin histology.
Naked-eye examination of the excised lumps correctly distinguished between benign and malignant tumours in 95·1% of cases with 23 (4·5%) false negative and two (0·4%) false positive results.
Rapid imprint cytodiagnosis was correct in 96·9% of the 391 lumps imprinted with 12 (3·1%) false negatives and no false positive results.
Frozen sections gave the correct diagnosis in 99·4% of the 510 cases with three (0·6%) false negative and no false positive results.
The use of cytology in the diagnosis of breast tumours is discussed.
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↵1 Present address: Department of Pathology, Southmead Hospital, Westbury-on-Trym, Bristol.