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A proposal for a standardized system of reporting human lymph node morphology in relation to immunological function
  1. H. Cottier,
  2. J. Turk,
  3. L. Sobin2
  1. Department of Pathology, University of Berne, Switzerland
  2. Department of Pathology, Royal College of Surgeons, London
  3. World Health Organization, Geneva


    This memorandum proposes a standardized system of reporting the histology of human lymph nodes based on commonly used simple staining techniques. The purpose is to provide a uniform, internationally acceptable system by which the histological structure of lymph nodes can be correlated with other parameters of immunological status. The proposed protocols are intended to provide information that is not available in conventional written reports that use such terms as `hyperplasia' or `nonspecific lymphadenitis'.

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    • 2 Requests for reprints should be addressed to Dr L. Sobin, WHO, 1211 Geneva, 27 Switzerland.

    • 1 Reprinted in slightly modified form, and with the addition of a bibliography, from Bulletin of the World Health Organization (1972), 47, 375-406.