Article Text

Download PDFPDF
Enzymes involved in phenylalanine metabolism in the human foetus and child
  1. Anne McLean,
  2. Margaret J. Marwick,
  3. Barbara E. Clayton
  1. Department of Chemical Pathology, The Hospital for Sick Children, Great Ormond Street, London
  2. Institute of Child Health, Guilford Street, London


    The activities of phenylalanine p-hydroxylase, tyrosine: alpha-ketoglutarate and phenylalanine: pyruvate aminotransferases, and aromatic alpha-ketoacid reductase have been measured in liver biopsies obtained from children with a series of disorders other than phenylketonuria and from human foetuses aged 8·5 to 24 weeks. The importance of such a study in relation to the management of infants with hyperphenylalaninaemia and pregnant phenylketonuric women is discussed

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.