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The cellular composition of the granulocyte series in the normal human bone marrow according to the volume of the sample
  1. C. Dresch1,
  2. A. Faille,
  3. O. Poirier,
  4. J. Kadouche
  1. Service de Médecine Nucléaire, Institut de Recherche sur les Maladies du Sang, Hôpital Saint-Louis, Paris, France


    The cellular composition of the granulocytic series in normal human bone marrow was studied in aspirates of different volume. An increase in the proportion of polymorphonuclears was observed in samples of more than 1 ml, thus indicating a dilution of bone marrow by peripheral blood. Certain data from the literature, referring to the differential count in the bone marrow granulocytic series, are discussed. The differences between these data can be explained by the dilution of bone marrow cells by mature granulocytes in blood.

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    • 1 Correspondence to: Doctor Catherine Dresch, maitre de Recherches, INSERM, Laboratoire de Médecine Nucléaire, Centre Hayem, Hôpital Saint-Louis, 2, Place du Docteur-Fournier, 75475, Paris, Cedex 10.