Article Text

Download PDFPDF

Separation of abnormal cells in the peripheral blood by means of the zonal centrifuge
  1. Patricia M. Egan1,
  2. J. V. Garrett,
  3. C. W. Gilbert
  1. Department of Pathology, Christie Hospital, Manchester
  2. Holt Radium Institute, Manchester
  3. Paterson Laboratories, Manchester


    The basic principles of rate centrifugation in the large volume zonal centrifuge and its application to the separation of abnormal or rarely occurring cells in the blood are described. Details of the method, gradient media, and collection and examination of the fractions obtained are given. A description of the cells found in normal human blood, in a subject undergoing known immunological stimulus, and in glandular fever and Hodgkin's disease is given and the implications are discussed.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


    • 1 Present address: Mathilda and Terence Kennedy Institute of Rheumatology, Bute Gardens, Hammersmith, London W6 7DW.