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Research Article
Effect of oral contraceptives on factor VIII clotting activity and factor VIII related antigen in normal women.
  1. P Stableforth,
  2. D C Montgomery,
  3. E Wilson,
  4. W G Churchill,
  5. K M Dormandy,
  6. R M Hardisty

    Abstract

    The factor VIII clotting activity (VIIIc1 and factor VIII related antigen (VIIIRAg) were determined repeatedly in 24 pairs of age-matched normal women, one of each pair being on oral contraceptives. No significant differences in either parameter or in the VIIIc/VIIIRAg ration were found between the two groups ,although the mean factor VIII clotting activity and VIIIc/VIIIRAg ratios for women on oral contraceptives were very slightly higher than for those not on oral contraceptives.

    https://doi.org/10.1136/jcp.28.6.498

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