We have recently utilized a prototype model of the Beckman Enzyme Activity Analyzer System-TR in our laboratory measuring various serum enzyme activities which include: alkaline phosphatase (ALP), E.C.188.8.131.52; creatine kinase (CK), E.C.184.108.40.206; hydroxybutyrate dehydrogenase (HBD), E.C.220.127.116.11; lactate dehydrogenase (LD), E.C.18.104.22.168; aspartate transaminase (AST), E.C.22.214.171.124; and alanine transaminase (ALT), E.C.126.96.36.199. Precision was found to be good. Sample activities could be measured as high as 1000 IU/1. The carryover studies fell within 2 SD of the means of the enzyme control studies. Coefficients of variation for ALP and CK were in the ranges of 0-40-2-14% and 0-52-4-30%, respectively. Correlation studies were done with GemSAEC and Gilford 300 N Spectrophotometer and the results were accurate, precise, and reproducible.
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