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Synergy between sulphonamide and trimethoprim in the presence of pus.
  1. P N Edmunds


    Synergy between sulphadiazine and trimethoprim against Escherichia coli has been demonstrated in culture media not containing lysed horse blood despite the presence of pus or a pus extract which inhibited the action of each drug separately. Synergy may therefore be important where pus is present in vivo.

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